%0 Journal Article
%T Manganese(III) Acetate-mediated Oxidative Cyclization of a-Methylstyrene and trans-Stilbene with b-Ketosulfones
%A Ahlem Bouhlel
%A Christophe Curti
%A Cl¨¦mence Tabel¨¦
%A Patrice Vanelle
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18044293
%X A convenient microwave irradiation protocol was utilized for the synthesis of b-ketosulfones 1¨C 5 in good yields. These sulfones reacted with alkenes through a radical oxidative cyclization mediated by Mn(OAc) 3. Dihydrofurans 6¨C 10 were obtained in moderate to good yields starting from 1,1-disubstituted alkenes. Dihydrofurans 11¨C 15 were synthesized in moderate yields and unexpected cyclopropanes 16¨C 19 were obtained in low yields starting from 1,2-disubstituted alkenes. This protocol offers access to various dihydrofurans which could be tested for their antiparasitic potential.
%K manganese(III) acetate
%K dihydrofuran
%K radicals
%U http://www.mdpi.com/1420-3049/18/4/4293