%0 Journal Article
%T Anti-inflammatory Lignans from the Fruits of Acanthopanax sessiliflorus
%A Dae-Young Lee
%A Kyeong-Hwa Seo
%A Rak-Hun Jeong
%A Sang-Min Lee
%A Geum-Soog Kim
%A Hyung-Jun Noh
%A Seung-Yu Kim
%A Gye-Won Kim
%A Ji-Young Kim
%A Nam-In Baek
%J Molecules
%D 2013
%I MDPI AG
%R 10.3390/molecules18010041
%X A new lignan, named acanthosessilin A ( 1), as well as eight known lignan and lignan glycosides 2- 9 were isolated from an ethanolic extract of Acanthopanax sessiliflorus fruits. The chemical structures were determined by spectroscopic methods, including HR-EIMS, 1D NMR ( 1H, 13C, DEPT), 2D NMR (gCOSY, gHSQC, gHMBC, NOESY), and IR spectroscopy. All isolated compounds were tested for the ability to inhibit LPS-induced nitric oxide production in RAW264.7 macrophages.
%K Acanthopanax sessiliflorus
%K lignan
%K acanthosessilin A
%K nitric oxide
%U http://www.mdpi.com/1420-3049/18/1/41