%0 Journal Article
%T Biology of Trypanosoma cruzi: An update Biolog¨ªa del Trypanosoma cruzi: Actualizaci¨®n
%A Andr¨¦ Vianna Martins
%A Andr¨¦ia Patr¨ªcia Gomes
%A Eduardo Gomes de Mendon£¿a
%A Juliana Lopes Rangel Fietto
%J Infectio
%D 2012
%I Asociacion Colombiana de Infectologia
%X Chagas disease, an illness caused by the protozoan Trypanosoma cruzi, is clinically and epidemiologically important in Latin America, and particularly in Brazil. This article presents the main biological characteristics of Trypanosoma cruzi, emphasizing ultrastructural, morphological, evolutionary, transcriptomic, and proteomic aspects. With this purpose a literature review was conducted, which allowed for the construction of different sections of the text. The efforts to expand the knowledge of this protist biology may bring positive implications for the understanding of the pathogenesis, control, and above all, treatment of patients affected by this disease. A mol¨¦stia de Chagas, enfermidade causada pelo protozo¨¢rio Trypanosoma cruzi, apresenta grande relevancia cl¨ªnica e epidemiol¨®gica na America Latina, com destaque para o Brasil. Neste artigo ser o apresentadas as principais caracter¨ªsticas biol¨®gicas do Trypanosoma cruzi, enfatizando-se os aspectos ultra-estruturais, morfol¨®gicos, evolutivos, transcript micos e prote micos. Para tanto, foi realizada revis o da literatura, a qual subsidiou a constru  o de diferentes se  es do texto. As investidas para ampliar o conhecimento acerca da biologia do protista poder o trazer implica  es positivas para a compreens o da patog¨ºnese, do controle e, sobretudo, do tratamento dos pacientes portadores da mol¨¦stia.
%K Trypanosoma cruzi
%K biologia
%K transcriptoma
%K proteoma
%K Trypanosoma cruzi
%K biology
%K transcriptome
%K proteome
%U http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0123-93922012000100008