%0 Journal Article
%T New prevalence estimate of TT virus (TTV) infection in low- and high-risk population from S o Paulo, Brazil
%A BASSIT Leda
%A TAKEI Kioko
%A HOSHINO-SHIMIZU Sumie
%A NISHIYA Anna S.
%J Revista do Instituto de Medicina Tropical de S£¿o Paulo
%D 2002
%I Instituto de Medicina Tropical
%X The prevalence of TT virus (TTV) infection was investigated by Polymerase Chain Reaction (PCR) in low- (blood donors and healthy children/adolescents) and high-risk (hemophiliacs) groups from S o Paulo, Brazil. Primers based on the untranslated region (UTR) of the viral genome proved to be much more ubiquitous, leading to much higher frequencies for both groups ( > or = 81%) than the earlier N22-PCR directed to the open reading frame 1 (blood donors, 5.5%, and hemophiliacs, 42.3%). The UTR-PCR also revealed an interesting profile for healthy children/adolescents: very high prevalence at the early years and significant decrease in male teenagers. The N22-PCR, in turn, demonstrated higher frequency in hemophiliacs treated with fresh blood products (58%), than in those treated with virus-inactivated clotting factors (9.4%) and blood donors (5.5%).
%K TT virus
%K Emergent viruses
%K Parenteral transfusion
%K Blood bank
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652002000400010