%0 Journal Article
%T EXTRACTION, BIOCHEMICAL CHARACTERIZATION AND ANTIMICROBIALACTIVITY OF FISH MUCUS.
%A M.A.DHOTRE
%A P.D..BANSODE
%A V.S.SHEMBEKAR
%J Indian Streams Research Journal
%D 2013
%I Laxmi Book Publication
%X Antimicrobial proteins and peptides play key roles in innate immunity and they had been observed from a wide variety of organisms in the last few years. The present study was undertaken to characterize antimicrobial peptides from the epidermal mucus of fishes collected from the Latur fish market. Antimicrobial properties of the fishes (Channa gachua, Channa punctatus, Cyprinus carpio and Arius dussumieri ) were tested against pathogenic bacteria and pathogenic fungi. The results of the present investigation reported that the mucus of the fishes having remarkable antimicrobial activity. In the present study efforts have been made to find the antimicrobial effect of the mucus of fresh water and river fishes namely Channa punctatus , Channa gachua, Cyprinus carpio and Arius dussumieri. Fish mucus was tested against pathogenic bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa, Staphylococcus aureus, A.niger and C. albicans. The molecular masses of the peptides were 15 kDa and 200kDa as determined by SDS- polyacrylamide gel electrophoresis. This peptide had shown very effective activity against various human pathogens. The present findings suggest that fish mucus has very good antimicrobial activity against pathogenic microbes.
%K SDS PAGE
%K Antimicrobial activity
%K fish skin mucus
%K fishes.
%U http://www.isrj.net/UploadedData/1803.pdf