%0 Journal Article
%T A prospective controlled study: Minimally invasive stereotactic puncture therapy versus conventional craniotomy in the treatment of acute intracerebral hemorrhage
%A Houguang Zhou
%A Yu Zhang
%A Ling Liu
%A Xu Han
%A Yinghong Tao
%A Yuping Tang
%A Wei Hua
%A Jianzhong Xue
%A Qiang Dong
%J BMC Neurology
%D 2011
%I BioMed Central
%R 10.1186/1471-2377-11-76
%X A prospective controlled study was undertaken. The clinical trial was in compliance with the WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects. According to the enrollment criterion, there were 168 acute ICH cases analyzed, of which 90 cases were performed by MISPT ( MISPT group, MG) and 78 cases by Conventional craniotomy (CC group, CG), by means of compare of Glasgow Coma Scale(GCS) score, postoperative complications(PC) and rebleeding incidence(RI), moreover, long-term outcome of 1 year postoperation judged by Glasgow Outcome Scale (GOS), Barthel Index (BI), modified Rankin Scale (mRS) and case fatality(CF).MG patients showed obvious amelioration in GCS score compared with that of CG. The total incidence of PC in MG decreased obviously compared with that of CG. The incidences of rebleeding in MG and CG were 10.0% and 15.4% respectively. There was no obvious difference between CFs of MG and CG. For three parameters representing long-term outcome, the GOS, BI and mRS in MG were ameliorated significantly than that of CG.These data suggested that the advantage of MISPT was displayed in minute trauma and safety, and seemed to be feasible and to had a trend towards improved long-term outcome.The Australian New Zealand Clinical Trials Registry (ANZCTR), the registration number:ACTRN12610000945022.Spontaneous intracerebral hemorrhage (ICH) comprises in 8-30% of all stroke victims, depending on regional and ethnic differences, and is a devastating form of stroke with the high mortality twofold to sixfold higher than that for ischemic stroke [1], and 1-year survival rate less than 50%[2]. Hitherto, morbidity and mortality following ICH remain the highest among all forms of cerebrovascular diseases, with a 30-day mortality rate of 35% to 52%, half of the deaths occurring in the first 2 days [3-5]. After initial irreversible tissue injury is suffered near the hemorrhage nidus, a progressive cascade of elevated local pressures, ede
%U http://www.biomedcentral.com/1471-2377/11/76