%0 Journal Article
%T Modelo experimental est¨¢vel de aneurisma sacular em art¨¦ria car¨®tida de su¨ªnos utilizando veia jugular interna Stable experimental model of carotid artery saccular aneurysm in swine using the internal jugular vein
%A Severino Louren£¿o da Silva J¨²nior
%A Guilherme Benjamin Brand£¿o Pitta
%A Adamastor Humberto Pereira
%A Aldemar de Ara¨²jo Castro
%J Revista do Col¨¦gio Brasileiro de Cirurgi£¿es
%D 2013
%I Col¨¦gio Brasileiro de Cirurgi?es
%X OBJETIVO: Desenvolver um modelo experimental est¨¢vel de aneurisma sacular em car¨®tida de su¨ªnos utilizando veia jugular interna. M¨¦TODOS: Em 12 su¨ªnos sadios, com peso variando entre 25 e 50kg, cinco machos e sete f¨ºmeas, foi confeccionado aneurisma na art¨¦ria car¨®tida comum direita. Ap¨®s arteriotomia el¨ªptica, foi realizada anastomose terminolateral com coto distal de veia jugular interna. O volume do aneurisma era calculado de maneira que o valor n o excedesse em 27 vezes o valor da ¨¢rea da arteriotomia. Ap¨®s seis dias, era realizada angiografia e an¨¢lise microsc¨®pica do aneurisma para avaliar perviedade e trombose parcial ou total. RESULTADOS: Houve ganho de peso significante dos su¨ªnos no intervalo de tempo entre a confec  o do aneurisma e a angiografia (p = 0,04). Foi observada perviedade aneurism¨¢tica em dez su¨ªnos (83%). Ocorreram infec  es de feridas operat¨®rias em dois animais (16,6%), ambas com in¨ªcio de aparecimento em tr¨ºs dias ap¨®s a confec  o do aneurisma. An¨¢lise histol¨®gica dos aneurismas mostrou trombos ocluindo parcialmente a luz em nove su¨ªnos (75%). Nesses animais, observou-se que, em m¨¦dia, 9% da luz aneurism¨¢tica estava preenchida por trombos. CONCLUS O: P de ser desenvolvido um modelo experimental est¨¢vel de aneurisma sacular em car¨®tida de su¨ªnos utilizando veia jugular interna. OBJECTIVE: To develop an experimental model of stable saccular aneurysm in carotid of pigs using the internal jugular vein. METHODS: In 12 healthy pigs, weighing between 25 and 50kg, five males and seven females, we made a right common carotid artery aneurysm. After elliptical arteriotomy, we carried out a terminolateral anastomosis with the distal stump of the internal jugular vein. Aneurysm volume was calculated so that the value did not exceed 27 times the area of the arteriotomy. After six days angiography and microscopic examination were performed to assess patency of the aneurysm and the presence of total or partial thrombosis. RESULTS: There was a significant weight gain of pigs in the time interval between the manufacture of the aneurysm and angiography (p = 0.04). Aneurysmal patency was observed in ten pigs (83%). Operative wound infections occurred in two animals (16.6%), both with early onset, three days after the making of the aneurysm. Histological analysis showed aneurysm thrombus partially occluding the light in nine pigs (75%). In these animals, it was observed that on average 9% of the aneurysmal diameter was filled with thrombi. CONCLUSION: It was possible to develop a stable experimental model of saccular aneurysms in pig carotid artery
%K Aneurisma
%K Veias jugulares
%K Art¨¦rias car¨®tidas
%K Experimenta  o animal
%K Su¨ªnos
%K Aneurysm
%K Jugular veins
%K Carotid arteries
%K Animal experimentation
%K Pigs
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912013000200009