%0 Journal Article
%T Functional neuro-imaging and post-traumatic olfactory impairment
%A Roberts Richard
%A Sheehan William
%A Thurber Steven
%A Roberts Mary
%J Indian Journal of Psychological Medicine
%D 2010
%I Medknow Publications
%X Objective: To evaluate via a research literature survey the anterior neurological significance of decreased olfactory functioning following traumatic brain injuries. Materials and Methods: A computer literature review was performed to locate all functional neuro-imaging studies on patients with post-traumatic anosmia and other olfactory deficits. Results: A convergence of findings from nine functional neuro-imaging studies indicating evidence for reduced metabolic activity at rest or relative hypo-perfusion during olfactory activations. Hypo-activation of the prefrontal regions was apparent in all nine post-traumatic samples, with three samples yielding evidence of reduced activity in the temporal regions as well. Conclusions: The practical ramifications include the reasonable hypothesis that a total anosmic head trauma patient likely has frontal lobe involvement.
%K Anosmia
%K functional neuro-imaging
%K olfaction
%K traumatic brain injury
%U http://www.ijpm.info/article.asp?issn=0253-7176;year=2010;volume=32;issue=2;spage=93;epage=98;aulast=Roberts