%0 Journal Article %T Phenotypical and Functional Analysis of Intraepithelial Lymphocytes from Small Intestine of Mice in Oral Tolerance %A Maristela Ruberti %A Luis Gustavo Romani Fernandes %A Patricia Ucelli Simioni %A Dirce Lima Gabriel %A ¨¢ureo Tatsumi Yamada %A Wirla Maria da Silva Cunha Tamashiro %J Clinical and Developmental Immunology %D 2012 %I Hindawi Publishing Corporation %R 10.1155/2012/208054 %X In this work, we evaluated the effects of administration of OVA on phenotype and function of intraepithelial lymphocytes (IELs) from small intestine of transgenic (TGN) DO11.10 and wild-type BALB/c mice. While the small intestines from BALB/c presented a well preserved structure, those from TGN showed an inflamed aspect. The ingestion of OVA induced a reduction in the number of IELs in small intestines of TGN, but it did not change the frequencies of CD8 %U http://www.hindawi.com/journals/cdi/2012/208054/