%0 Journal Article %T VALIDATION OF A METHODOLOGY FOR INPATIENT PHARMACOTHERAPY FOLLOW-UP VALIDACION DE UNA METODOLOG¨ªA PARA EL SEGUIMIENTO FARMACOTERAPEUTICO EN PACIENTE HOSPITALIZADO %A Jes¨²s BECERRA C. %A Fernando MARTINEZ M. %A Martha BOHORQUEZ C. %A Martha L GUEVARA U. %J Vitae %D 2012 %I Universidad de Antioquia %X Background: Pharmacotherapy follow-up is a practice in which the pharmacist assumes responsibility for the patient's drug-related Problems. Its goal is to achieve positive clinical outcomes. Methods to perform pharmacotherapy follow-up have centered principally on ambulatory patients. Objective: The purpose of this study is to propose and validate a methodology for inpatient pharmacotherapy follow-up. Methods: A systematic review was performed. This consisted in a comprehensive search of databases containing studies published in English or Spanish during 1998 - 2008, and that sought to improve the transfer of accurate information about Pharmacotherapy follow-up in inpatients. The key terms used to conduct the search were identified in consultation with clinical experts and included: Pharmacotherapy follow-up methods, pharmacotherapy follow-up, drug therapy problems, and validation. A comparative table was elaborated to differentiate and evaluate the advantages of each of the proposed methodologies. The information gathered allowed to propose a sequence of general steps for inpatient Pharmacotherapy follow-up. To validate the methodology, a descriptive study was carried out with 32 randomly selected patients and was independently followed up by two pharmacists to assess the reproducibility of the process. Results: Pharmaceutical Care Practice: The Clinician's Guide, proposed by Cipolle & Strand. Applied Therapeutics: The Clinical Use of Drugs, the D¨¢DER method, and the IASER program, were selected. 79 drug therapy problems (DTPs) were identified and resolved, where errors in necessity of medication had the highest incidence (46.6%), followed by effectiveness (24.5%) and safety (28.9%). The degree of agreement among researchers in the identification and resolution of DTPs was quantified using the kappa coefficient, showing a high concordance (90% CI). The Fisher's exact test determined that DTPs are related to the duration of the follow up, number of medications, length of the stay and previous hospitalizations. Conclusions: The methodology allows identifying, preventing and resolving DTPs. It proved to be reproducible and have a high degree of concordance between applications. Antecedentes: El Seguimiento Farmacoterap¨¦utico es la pr¨¢ctica profesional donde el farmac¨¦utico asume la responsabilidad de la medicaci¨®n del paciente con el objetivo de obtener resultados cl¨ªnicos positivos. Los m¨¦todos actuales para realizar Seguimiento Farmacoterap¨¦utico se han centrado principalmente en pacientes ambulatorios. Objetivos: Proponer y validar una metodolog¨ªa de Se %K Atenci¨®n Farmac¨¦utica %K farmac¨¦utico %K paciente hospitalizado %K validaci¨®n %K Pharmaceutical care %K pharmacists %K inpatient %K validation %U http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-40042012000300004