%0 Journal Article
%T Lantana montevidensis Briq improves the aminoglycoside activity against multiresistant Escherichia coli and Staphylococcus aureus
%A Sousa Erlanio
%A Almeida Thiago
%A Rodrigues Fab¨ªola
%A Campos Adriana
%J Indian Journal of Pharmacology
%D 2011
%I Medknow Publications
%X Objective : In this work, we report the antibacterial and modulatory activity of Lantana montevidensis Briq. Materials and Methods : The antibacterial activities of leaf (LELm) and root (RELm) extracts alone or in association with aminoglycosides were determined by a microdilution test. Multiresistant strains of Escherichia coli (Ec 27) and Staphylococcus aureus (Sa 358) were used. Results : The results show the inhibitory activity of LELm against E. coli (minimal inhibitory concentration [MIC] 16 ¦Ìg/mL) and S. aureus (MIC 128 ¦Ìg/mL). The synergistic effect of the extracts and aminoglycosides was verified too. The maximum effects were obtained with RELm with gentamicin against E. coli with MIC reduction (312 to 2 ¦ÌL). Conclusion : The data from this study are indicative of the activity antibacterial of extracts of L. montevidensis and its potential in modifying the resistance of aminoglycosides.
%K Aminoglycosides
%K antibacterial and modulatory activities
%K Lantana montevidensis Briq
%U http://www.ijp-online.com/article.asp?issn=0253-7613;year=2011;volume=43;issue=2;spage=180;epage=182;aulast=Sousa