%0 Journal Article
%T RP-HPLC method for the estimation of dutasteride in tablet dosage form
%A Patel Dipti
%A Patel N
%A Patel S
%A Prajapati A
%J Indian Journal of Pharmaceutical Sciences
%D 2010
%I Medknow Publications
%X A simple, sensitive and precise RP-HPLC method was developed for the determination of dutasteride in tablet dosage form. The RP-HPLC separation was achieved on phenomenex C 18 column (250 mm, id 4.6 mm, 5 ¦Ìm) using mobile phase methanol:water (90:10 v/v) at a flow rate of 1 ml/min at an ambient temperature. Quantification was achieved with photodiode array detection at 235 nm over the concentration range 1-12 ¦Ìg/ml. The method was validated statistically and was applied successfully for the determination of dutasteride in tablets.
%K Benign prostatic hyperplasia
%K dutasteride
%K RP-HPLC
%U http://www.ijpsonline.com/article.asp?issn=0250-474X;year=2010;volume=72;issue=1;spage=113;epage=116;aulast=Patel