%0 Journal Article
%T Evaluation of central nervous system depressant activity of Cleome rutidosperma
%A Anindya Bose
%A Anuradha Khuntia
%A Jayanta Kumar Gupta
%A Sudam Si
%J Alternative Medicine Studies
%D 2012
%I 
%R 10.4081/ams.2012.e8
%X The central nervous system (CNS) depressant activity of the ethanol extract (200 and 400 mg/kg) and its fractions (200 mg/kg each) of the aerial parts of Cleome rutidosperma was investigated in various models. The tested extract and its fractions showed significant (P<0.01) anxiolytic, anticonvulsant activity (in treating petit mal epilepsy) without any unwanted sedation effect. These findings justify the traditional use of this plant in CNS disorders.
%K Cleome rutidosperma
%K CNS
%K anticonvulsant
%K potentiation
%K muscle relaxant
%K anti-anxiety
%U http://www.pagepress.org/journals/index.php/ams/article/view/3660