%0 Journal Article
%T Anti-inflammatory activity of Syzygium cumini leaf against experimentally induced acute and chronic inflammations in rodents
%A Anirban Roy
%A Sanjib Bhattacharya
%A Jitendra N. Pandey
%A Moulisha Biswas
%J Alternative Medicine Studies
%D 2011
%I 
%R 10.4081/ams.2011.e6
%X Syzygium cumini (L.) Skeels (Myrtaceae), commonly known as Jam in Bengali, Jamun in Hindi and Black Plum or Black Berry in English, is a large size evergreen tree indigenous to India and is cultivated for its fruits. In the present study, the methanol extract of leaves from S. cumini (MESC) was evaluated for anti-inflammatory activity in experimental acute (carrageenan, histamine and serotonin induced rat paw oedema) and chronic models (cotton pellet induced rat granuloma). In all models, the MESC (100 and 200 mg/kg body wt. p.o.) exhibited significant anti-inflammatory activity (p < 0.001) in a dose dependent manner. These findings revealed that the S. cumini leaf had remarkable acute and chronic anti-inflammatory actions in the tested rodent models.
%K Anti-inflammatory
%K chronic
%K mediators
%K Syzygium cumini
%K leaf.
%U http://www.pagepress.org/journals/index.php/ams/article/view/2624