%0 Journal Article
%T Calcium phosphate ceramics as bone graft substitutes in filling bone tumor defects
%A Saikia K
%A Bhattacharya T
%A Bhuyan S
%A Talukdar D
%J Indian Journal of Orthopaedics
%D 2008
%I Medknow Publications
%X Background: Synthetic bio-inert materials are currently used as an alternative to autogenous bone graft. Calcium hydroxyapatite (HA) and Beta tri-calcium phosphate (¦Â-TCP), which belong to the calcium phosphate ceramics group, are biocompatible and osteo-conductive. The purpose of this study is to analyse the use of HA and ¦Â-TCP in their ceramic forms as a bone graft substitute in filling bone voids after curettage of benign bone tumors. Materials and Methods: Twenty-four patients in the age range of 3.5-55 years (mean 14.3 years) having benign bone tumors with bone defects were filled with bone graft substitute following curettage. In 20 patients bone defects were filled with block/granules of HA ceramic and in four with ¦Â-TCP. Fibular strut graft was packed with HA in four patients. The patients were followed up for an average of 18 months (range 12-36 months). Results: The functional status of the patients at follow-up was evaluated and compared with preoperative functional status. Early incorporation of graft substitutes became evident radiologically between 6 and 10 weeks (Stage I). Complete incorporation (Stage III) was observed in an average of nine months (6-18 months). Clinical healing was observed before radiological healing. The average time taken to return to preoperative function was 14 weeks. There was no recurrence of lesion or growth retardation. Conclusion: Calcium hydroxyapatite and ¦Â-TCP are excellent bone graft substitutes for autogenous bone graft in filling voids after curettage of benign bone tumors.
%K Benign bone tumor
%K bone graft substitute
%K hydroxyapatite
%K calcium phosphate ceramic
%U http://www.ijoonline.com/article.asp?issn=0019-5413;year=2008;volume=42;issue=2;spage=169;epage=172;aulast=Saikia