%0 Journal Article
%T Nonsecretory multiple myeloma
%A Middela Seshikanth
%A Kanse Prakash
%J Indian Journal of Orthopaedics
%D 2009
%I Medknow Publications
%X Multiple myeloma is characterized by clonal proliferation of plasma cells usually of the B cell type.The skeletal manifestations are usually osteolytic lesions whose differential diagnosis includes primary and secondary bone tumor. This tumor is characterized by the presence of abnormal paraprotein 8 in blood and urine. However, one to five per cent of the cases do not have any protein. Hence they are termed nonsecretory. It often poses a diagnostic dilemma when it is presented to orthopedic surgeons with no clear features of the disease. Our case report exemplifies such a diagnostic dilemma. A high index of suspicion must be borne in mind when excluding multiple myeloma as a cause of pain, pathological fracture or lytic lesion.
%K Multiple myeloma
%K non secretory
%K bone tumor
%U http://www.ijoonline.com/article.asp?issn=0019-5413;year=2009;volume=43;issue=4;spage=408;epage=411;aulast=Middela