%0 Journal Article
%T Osteopoikilosis: A Sign Mimicking Skeletal Metastases in a Cancer Patient
%A Sepideh Sefidbakht
%A Yaghoub Ashouri-Taziani
%A Sareh Hoseini
%A Mansour Ansrai
%J Middle East Journal of Cancer
%D 2011
%I Shiraz University of Medical Sciences
%X Osteopoikilosis is a rare benign osteosclerotic bone disorder that may be misdiagnosed as skeletal metastases. Here we describe a case of coincidental breast cancer and osteopoikilosis mimicking skeletal metastases. A 41-year-old woman underwent right modified radical mastectomy in April 2007. Twenty-eight months after initial treatment,the patient complained of bilateral knee and foot pain. Plain X-rays of the feet and knees showed multiple well-defined osteosclerotic lesions. According to the radiographic appearance, the most likely differential diagnoses included skeletal metastases from breast cancer and osteopoikilosis. A whole-body bone scintigraphy showed no increase in uptake by the sclerotic lesions, and serum lactic dehydrogenase, carcinoembryonic antigen, alkaline phosphatase and cancer antigen 15-3 were not elevated. We therefore diagnosed the patient¡¯s skeletal lesions as osteopoikilosis. This case and ourliterature review suggest that the radiographic appearance of osteopoikilosis may mimic or mask skeletal metastases, potentially leading to misdiagnosis in patients with cancer.
%K Osteopoikilosis
%K Osteosclerotic
%K Skeletal metastases
%K Breast cancer.
%U http://mejc.sums.ac.ir/index.php/mejc/article/view/47/126