%0 Journal Article %T Intravitreal anti-vascular endothelial growth factor agents as an adjunct in the management of Coats¡ä disease in children %A Kaul Shalini %A Uparkar Mahesh %A Mody Kruti %A Walinjkar Jaydeep %J Indian Journal of Ophthalmology %D 2010 %I Medknow Publications %X We describe the role of intravitreal anti-vascular endothelial growth factor (VEGF) agents in Coats¡ä disease in children. In a prospective, interventional, non-randomized case series, three patients (three eyes) aged 16, seven and two years were diagnosed to have Coats¡ä disease. In Case 1 (16 yr/ male) with macular edema, previous laser photocoagulation being unsuccessful, intravitreal pegaptanib sodium (Macugen ) was tried. Case 2 (seven yr/ male) and Case 3 (two yr/ female) were diagnosed to have Stage 4 Coats¡ä and underwent external needle drainage, laser photocoagulation, SF6 gas injection and intravitreal injection of bevacizumab (Avastin ). Reduction of exudation and attached posterior pole (Cases 2 and 3) was seen at a follow-up of six months and two months respectively. Intravitreal anti-VEGF agents may be successfully used as adjunct treatment in select cases of Coats¡ä disease in childhood. %K Coats¡ä disease %K vascular endothelial growth factor %U http://www.ijo.in/article.asp?issn=0301-4738;year=2010;volume=58;issue=1;spage=76;epage=78;aulast=Kaul