%0 Journal Article %T Coats¡ä disease: An Indian perspective %A Rishi Pukhraj %A Rishi Ekta %A Uparkar Mahesh %A Sharma Tarun %J Indian Journal of Ophthalmology %D 2010 %I Medknow Publications %X Aim: To describe the clinical features, treatment and outcome patterns in 307 eyes with Coats¡ä disease. Materials and Methods: Retrospective chart review of patients diagnosed with Coats¡ä disease between January 1996 and January 2006 from a single referral center in southern India. Results: Two hundred and eighty patients (307 eyes) with mean age of 15.67 years (range: Four months-80 years) were included. Decreased vision (77%), unilateral affection (90%) and male preponderance (83.4%) were chief presenting features. Anterior segment involvement was seen in 67 (21.8%) eyes. Retinal telangiectasia were seen in 302 (99%) eyes, exudation in 274 (89%) eyes and retinal detachment in 158 (51.5%) eyes. Four-quadrant disease was seen in 207 (67.2 %) eyes. Visual acuity was < 20/200 in 249 (80.9%) eyes. One hundred and nine of 176 treated eyes (61.93%) had favorable anatomical outcome; 207 of 280 eyes (74%) had an optimal structural outcome. Seventeen (5.3%) eyes were enucleated. Complications following treatment included phthisis bulbi (7%), neovascular glaucoma (5%), epiretinal membrane (4.4%) and rubeosis iridis (4.4%). Conclusion: Indian patients with Coats¡ä disease have a high male predominance, the majority of whom present with severe visual impairment and extensive four-quadrant exudation. Unusual presentations such as pain, vitreous hemorrhage and a high incidence of anterior segment involvement are distinctive to Indian eyes. %K Children %K Coats¡ä disease %K cryotherapy %K laser photocoagulation %K macular edema %K retinal detachment %K retinal telangiectasia %U http://www.ijo.in/article.asp?issn=0301-4738;year=2010;volume=58;issue=2;spage=119;epage=124;aulast=Rishi