%0 Journal Article
%T BODE-Index vs HADO-Score in Chronic Obstructive Pulmonary Disease: Which one to use in general practice?
%A Crist¨®bal Esteban
%A Jos¨¦ M Quintana
%A Javier Moraza
%A Myriam Aburto
%A Urko Aguirre
%A Jos¨¦ I Aguirregomoscorta
%A Susana Aizpiri
%A Luis V Basualdo
%A Alberto Capelastegui
%J BMC Medicine
%D 2010
%I BioMed Central
%R 10.1186/1741-7015-8-28
%X This is a prospective longitudinal study. During one year (2003 to 2004), 543 consecutively COPD patients were recruited in five outpatient clinics and followed for three years. The endpoints were all-causes and respiratory mortality.In the multivariate analysis of patients with FEV1 < 50%, no significant differences were observed in all-cause or respiratory mortality across HADO categories, while significant differences were observed between patients with a lower BODE (less severe disease) and those with a higher BODE (greater severity). Among patients with FEV1 ¡İ 50%, statistically significant differences were observed across HADO categories for all-cause and respiratory mortality, while differences were observed across BODE categories only in all-cause mortality.HADO-score and BODE-index were good predictors of all-cause and respiratory mortality in the entire cohort. In patients with severe COPD (FEV1 < 50%) the BODE index was a better predictor of mortality whereas in patients with mild or moderate COPD (FEV1 ¡İ 50%), the HADO-score was as good a predictor of respiratory mortality as the BODE-index. These differences suggest that the HADO-score and BODE-index could be used for different patient populations and at different healthcare levels, but can be used complementarily.Forced expiratory volume in one second (FEV1) is an essential measure for diagnosing chronic obstructive pulmonary disease (COPD) and in establishing its severity and prognosis. Traditionally, the two most important prognostic factors in the COPD have been FEV1 and age [1,2]. Other variables, such as dyspnea [3], malnutrition [4], hospitalization related to COPD exacerbation [5], exercise capacity [6], physical activity [7], pulmonary hypertension [8], inspiratory capacity [9], lung density measurements by computed tomography [10], muscle mass [11], health-related quality of life [12], and other markers [13], have also proved to be individual, effective prognostic factors.Simultaneously employ
%U http://www.biomedcentral.com/1741-7015/8/28