%0 Journal Article %T Extended spectrum -lactamases in urinary isolates of escherichia coli and klebsiella pneumoniae - Prevalence and susceptibility pattern in a tertiary care hospital %A Babypadmini S %A Appalaraju B %J Indian Journal of Medical Microbiology %D 2004 %I Medknow Publications %X A total of 411 urinary isolates (353 Escherichia coli and 58 Klebsiella pneumoniae) were studied for extended spectrum -lactamase (ESBL) production by double disk approximation test and NCCLS confirmatory test. ESBL production was found to be 41% in E.coli and 40% in K.pneumoniae. Fourteen percent and 12% of ESBL producers showed false susceptibility to ceftazidime and cefotaxime in routine susceptibility testing. The susceptibility of ESBL producers to imipenem, nitrofurantoin and amikacin was found to be 100%, 89% and 86% respectively. A high degree of associated resistance to gentamicin, co-trimoxazole and quinolones was found in ESBL producers. Majority of ESBL producers was detected among patients admitted in medical ICU and surgery ward. %K ESBL %K Escherichia coli %K Klebsiella pneumoniae %U http://www.ijmm.org/article.asp?issn=0255-0857;year=2004;volume=22;issue=3;spage=172;epage=174;aulast=Babypadmini