%0 Journal Article
%T A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience
%A Trivedi P
%A Patel P
%A Brahmbhatt M
%A Patel B
%J Indian Journal of Human Genetics
%D 2009
%I Medknow Publications
%X We report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.
%K Acute myeloid leukemia-M1
%K recurrent
%K sole abnormality
%K trisomy 13
%U http://www.ijhg.com/article.asp?issn=0971-6866;year=2009;volume=15;issue=3;spage=137;epage=139;aulast=Trivedi