%0 Journal Article
%T Oral Leucoplakia
%A Jain R
%A Kumar M
%A Nath O
%J Indian Journal of Dermatology, Venereology and Leprology
%D 1995
%I Medknow Publications
%X Oral leucoplakia was predominantly seen in elderly age group. Addiction to tobacco was observed in majority of patients (80.8%). Clinically commonest site of involvement was buccal mucosa (67.33%), followed by labial mucosa (13.86%). Majority of patients (57.35%) were having homogenous type of leucoplakia, followed by verrucous variety (25%). 26-48% cases were also having oral submucous fibrosis. Histologically various combinations of hyperkeratosis, hyperorthokeratosis and acanthosis were observed in 77.93% of cases. Dysplastic lesions were reported in 17.65% cases. In 80% of dysplastic lesions, band like infiltrate of mononuclear cells in subepithelial zone was seen. Malignant transformation was noticed in 2.94% cases. Excellent therapeutic results were obtained by cryosurgery. In resistant cases good results were observed with high dosage of vitamin A.
%K Oral leucoplakia
%K Epidemiology
%K Histology
%K Vitamin A
%K Cryosurgery
%U http://www.ijdvl.com/article.asp?issn=0378-6323;year=1995;volume=61;issue=6;spage=339;epage=341;aulast=Jain