%0 Journal Article
%T Explorative study on the use of omalizumab in patients suffering from interstitial cystitis/bladder pain syndrome
%A Daniele Porru
%A Enrica Bucchioni
%A Marcello Macchi
%A Fabio Leva
%J Urogynaecologia International Journal
%D 2012
%I 
%R 10.4081/uij.2012.e8
%X The aim of this study was to evaluate the efficacy of omalizumab in the treatment of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS), evaluated by visual analogue score for pain and urgency- frequency, OˇŻLeary-Sant IC symptom and problem index questionnaire, Pain Urgency Frequency questionnaire and Patient Global Assessment questionnaire. Four female patients with a diagnosis of IC/BPS were included in the study, with an age between 20 and 39 years. In the first patient the subjective final evaluation was of a marked improvement. The second patient had a moderate improvement of the subjective final evaluation. The third patient considered her overall clinical situation to have slightly improved after treatment. One 32-year-old patient, with multiple allergies, discontinued treatment after 3 months and could not complete the study due to side effects. Omalizumab was subcutaneously administered to patients with IC/PBS; it induced both a subjective and objective improvement of symptoms in 2 patients enrolled in the study.
%K anti-IgE treatment
%K interstitial cystitis/ bladder pain syndrome
%K omalizumab.
%U http://www.urogynaecologia.it/index.php/uij/article/view/112