%0 Journal Article %T A case control study of cardiovascular health in chemical war disabled Iranian victims %A Rohani Atoosheh %A Akbari Vahid %A Moghadam Fatemeh %J Indian Journal of Critical Care Medicine %D 2010 %I Medknow Publications %X Background: Sulfur mustard (SM) is an alkylating chemical warfare agent that was widely used during Iran-Iraq war between 1983 and 1988. SM exposure leads to various late complications. The aim of this study was to determine the late cardiovascular effects of SM in war-disabled Iranian victims. Materials and Methods: This was a retrospective cohort case control study on 50 patients with symptoms of SM exposure and 50 cases who had been in Iran-Iraq war, without chemical injury. We performed exercise stress test and echocardiography for all of patients. Results: The study group comprised 100 males of mean age 45.6 ¡À 6.2 years. In chemical war injury group, two patients (4%) had positive exercise stress test. On coronary angiography, they were found to have coronary artery disease. One patient had severe mitral regurgitation and normal coronary angiography; he was referred for mitral valve replacement. Left ventricular (LV) diastolic abnormality was detected in 23% of these subjects. In another group, 5% had LV diastolic abnormality (P = 0.02) and all of them had normal stress test. Conclusions: Cardiovascular abnormalities are another late complication in chemical war disabled Iranian victims. Diastolic dysfunction was the most common abnormality in both groups of patients. %K Cardiovascular abnormalities %K chemical warfare %K mustard gas %U http://www.ijccm.org/article.asp?issn=0972-5229;year=2010;volume=14;issue=3;spage=109;epage=112;aulast=Rohani