%0 Journal Article
%T Drug interaction leading to prolonged sedation in a postoperative high risk coronary bypass surgery patient
%A Bobade Shrikant
%A Kulkarni Vinay
%A Dhumne Sudhir
%A Barde Saurabh
%J Indian Journal of Critical Care Medicine
%D 2011
%I Medknow Publications
%X Use of midazolam infusion in mechanically ventilated patient is an established practice in critical care. In our case, the use of erythromycin as a prokinetic agent for better tolerance of enteral feeding and paralytic ileus led to an interaction between midazolam and erythromycin, which resulted in prolonged and deeply sedated patient. In a critically ill patient, there is always a possibility of multiple drug interactions. It is important to understand them and they should be considered before starting new medication.
%K Erythromycin
%K midazolam
%K prolonged sedation
%U http://www.ijccm.org/article.asp?issn=0972-5229;year=2011;volume=15;issue=1;spage=55;epage=57;aulast=Bobade