%0 Journal Article %T Early occurrence of acute myeloid leukemia following adjuvant radiotherapy and higher cumulative dose of cyclophosphamide in carcinoma breast %A Srivastava A %A Murari M %A Datta N %J Indian Journal of Cancer %D 2004 %I Medknow Publications %X We report a case of cancer breast developing acute myeloid leukemia (AML) within a relatively short interval of two and a half years of her primary treatment. This could be attributed to post operative radiotherapy and a higher cumulative dose of cyclophosphamide (14.4 gm) which had to be given as a part of her combination chemotherapy regimen, initially as adjuvant and then later as salvage chemotherapy. The successful salvage therapy for secondary AML instituted in this case is also discussed. %K Cancer breast %K Leukemia %K Chemotherapy %K Radiotherapy %K Second malignancy %U http://www.indianjcancer.org/article.asp?issn=0019-509X;year=2004;volume=41;issue=4;spage=178;epage=180;aulast=Srivastava