%0 Journal Article
%T 5-Fluorouracil-associated bradycardia: case report
%A Muhammet Ali KAPLAN
%A Timu£¿in £¿£¿L
%A Abdurrahman I£¿IKDO£¿AN
%J Turkish Journal of Oncology
%D 2010
%I KARE Publishing
%X 5-Fluorouracil (5-FU) is a synthetic, fluorinated pyrimidine antagonist, which is a cytostatic agent. Cardiotoxicity is a rare but important side effect of 5-FU. The cardiotoxicity incidence of 5-FU is increasing in conjunction with its frequent use in chemotherapy protocols. Ischemic symptoms and signs related to 5-FU are observed during the late phase of the drug administration. Monitoring should be done in all patients having coronary artery disease. There are many treatment options and prophylactic modalities for 5-FU cardiotoxicity. Herein, we present the rare case of a patient with cardiotoxicity during short 5-FU infusion.
%K Bradycardia
%K chemotherapy
%K 5-fluorouracil.
%U http://onkder.org/pdf.php3?id=757