%0 Journal Article
%T Are cup-like blasts specific to AML patients with FLT3 ITD and a normal karyotype? An ALL case report and review of the literature
%A £¿zg¨¹r Mehtap
%A Elif Birta£¿ Ate£¿o£¿lu
%A Emel G£¿n¨¹ll¨¹
%A Hakan Keski
%J Turkish Journal of Hematology
%D 2011
%I Galenos Yayinevi
%X Cup-like morphology is defined as cup-like nuclear invagination spanning ¡Ý25% of the nuclear diameter in >10% of blasts. Studies have shown that FLT3 ITD and normal cytology are strongly associated with cup-like morphology in acute myeloid leukemia (AML) patients. Herein we describe a patient with cup-like blasts that was diagnosed and treated for common acute lymphoblastic leukemia (ALL). In contrast to the literature, the presented case was Philadelphia chromosome positive and FLT3 ITD negative.
%K ALL
%K AML
%K cup-like blast
%K FLT3 ITD
%U http://www.journalagent.com/z4/download_fulltext.asp?pdir=tjh&plng=eng&un=TJH-57614