%0 Journal Article
%T A Case Report: Cushing¡¯s Disease Presenting with Polycythemia and Venous Thromboembolism
%A £¿nan Anaforo£¿lu
%A Kerem Ersoy
%A Ekrem Alg¨¹n
%A Ahmet Durmu£¿
%J Turkish Journal of Endocrinology and Metabolism
%D 2012
%I Galenos Yayincilik
%X We present the case of a woman with Cushing¡¯s disease who had originally received a diagnosis of primary polycythemia. Her major complaints were headache, weakness, and blushing of the face. She had been admitted to another hospital about 6 months previously for same symptoms, and she received a diagnosis of polycythemia vera. Before planned bone marrow aspiration and biopsy could be performed, the patient developed a popliteal vein thrombosis; heterozygotic mutation of factor V Leiden (1691 GA) had been identified. She was admitted to our hospital for bone marrow biopsy. Considering her physical examination and medical history which revealed facial plethora, moon-face, supraclavicular fullness, central obesity, purple striae at her abdomen, shoulder, and thighs, in addition to frontal balding, acne, hirsutism and infertility, she was evaluated for possible Cushing¡¯s disease. A diagnosis of Cushing¡¯s disease was made. Her haematological situation and clinical symptoms resolved after she underwent hypophysectomy for Cushing¡¯s disease. Cushing¡¯s disease is a possible cause of secondary erythrocytosis. Venous thrombosis can occur during the course of both Cushing¡¯s syndrome and primary polycythemias. It is important to exclude such secondary causes of polycythemia before making a final diagnosis. Turk Jem 2012; 16: 43-5
%K Cushing¡¯s disease
%K polycythemia
%K venous thromboembolism
%U http://www.turkjem.org/eng/makale/786/75/Full-Text