%0 Journal Article
%T Analysis of Prognostic Factors in Stage IIIB-IV Non-Small Cell Lung Cancer Cases who Received Chemotheraphy
%A Sibel Ar£¿n£¿
%A Nuray Erdal
%A Ferah Ece
%A Nilg¨¹n Hatabay
%J Turk Toraks Dergisi
%D 2010
%I Aves Yayincilik
%X Objective: Prognostic factors which influence survival which are definitive in the advanced stage of lung cancer cases are described. Material and Method: In this study, 193 stage IIIB-IV non-small cell lung cancer (NSCLC) outpatients who were followed up in our hospital¡¯s oncology department between January 2000 and September 2007 were retrospectively analysed. The effects of demographic, clinical and laboratory findings on survival were investigated.Results: Of the cases, 170 (88.02%) were men, 23(11.92%) were women and mean age was 57.44¡À9.42 years. Analysis by the Kaplan-Meier method revealed that mean survival was 13.8¡À10.8 months. A ECOG performance status of (0), younger than 65 age, no comorbid disease and normal LDH levels were found to be significantly important factors for long term survival (p=0.01, 0.003, 0.04, 0.003). Among metastases, bone metastasis was found to be a poor prognostic factor (p=0.01). However, anemia, leucocytosis, smoking status, weight loss and pleural effusion were not prognostic factors for survival. A multivariate analysis by Cox regression method revealed that normal LDH levels (p=0.01), <65 age (p=0.008), zero ECOG performance status (p=0.009) were independent prognostic factors in stage IIIB-IV lung cancer cases.Conclusion: Good ECOG performance status, normal LDH levels and <65 age play important roles in longer survival with advanced non-small cell lung cancer cases.
%K Non-small cell lung cancer
%K prognostic factors
%K advanced stage
%U http://www.toraks.org.tr/journal/text.php3?id=686