%0 Journal Article %T What is preventable harm in healthcare? A systematic review of definitions %A Mohammed Nabhan %A Tarig Beraima Elraiyah %A Daniel R Brown %A James A Dilling %A Annie LeBlanc %A Victor M Montori %A Timothy I Morgenthaler %A James M Naessens %A Larry J Prokop %A Veronique L Roger %A Stephen J Swensen %A Rodney L Thompson %A M. Hassan Murad %J BMC Health Services Research %D 2012 %I BioMed Central %R 10.1186/1472-6963-12-128 %X We conducted a comprehensive electronic search of relevant databases from January 2001 to June 2011 for publications that reported a definition of preventable harm. Only English language publications were included. Definitions were coded for common concepts and themes. We included any study type, both original studies and reviews. Two reviewers screened the references for eligibility and 28% (127/460) were finally included. Data collected from studies included study type, description of the study population and setting, and data corresponding to the outcome of interest. Three reviewers extracted the data. The level of agreement between the reviewers was calculated.One hundred and twenty seven studies were eligible. The three most prevalent preventable harms in the included studies were: medication adverse events (33/127 studies, 26%), central line infections (7/127, 6%) and venous thromboembolism (5/127, 4%). Seven themes or definitions for preventable harm were encountered. The top three were: presence of an identifiable modifiable cause (58/132 definitions, 44%), reasonable adaptation to a process will prevent future recurrence (30/132, 23%), adherence to guidelines (22/132, 16%). Data on the validity or operational characteristic (e.g., accuracy, reproducibility) of definitions were limited.There is limited empirical evidence of the validity and reliability of the available definitions of preventable harm, such that no single one is supported by high quality evidence. The most common definition is ˇ°presence of an identifiable, modifiable cause of harmˇ±. %K Preventable harm %K Systematic review %K Healthcare delivery %K Safety %U http://www.biomedcentral.com/1472-6963/12/128/abstract