%0 Journal Article
%T The impact of cognitive functioning on mortality and the development of functional disability in older adults with diabetes: the second longitudinal study on aging
%A Lisa C McGuire
%A Earl S Ford
%A Umed A Ajani
%J BMC Geriatrics
%D 2006
%I BioMed Central
%R 10.1186/1471-2318-6-8
%X Participants included 559 US adults (232 males and 327 females) ¡Ý 70 years old who had diabetes and who were free from cognitive impairment were examined using an adapted Telephone Interview of Cognitive Status (TICS), Activities of Daily Living (ADL), and Instrumental Activities of Daily Living (IADL).Multivariate logistic regression was conducted to investigate the independent contribution of cognitive functioning to three mutually exclusive outcomes of death and two measures of functional disability status. The covariates included in the model were participants' sex, age, race, marital status, educational level, duration of diabetes, cardiovascular disease (CVD) status, and self-rated health. Persons with diabetes who had the lowest levels of cognitive functioning relative to the highest level of cognitive functioning had a greater odds of dying (AOR = 0.80, 95% CI = 0.67¨C0.96) or becoming disabled (AOR = 0.87, 95% CI = 0.78¨C0.97) compared to those people who were disability free.Older adults with diabetes and low normal levels of cognition, yet within normal ranges, were approximately 20% more likely to die and 13% more likely to become disabled than those with higher levels of cognitive functioning over a 2-year period. Brief screening measures of cognitive functioning could be used to identify older adults with diabetes who are at increased risk for mortality and functional disability, as well as those who may benefit from interventions to prevent or minimize further disablement and declines in cognitive functioning.Cognitive dysfunction appears to be an additional complication of diabetes [1]. Accelerated declines in cognitive functioning have been consistently reported for older and middle-aged adults with diabetes [1-9]. In a recent systematic analysis, Cukierman and colleagues concluded that people with diabetes had a 1.2 to 1.5-fold greater change over time in measures of cognitive functioning and that the odds of future dementia was increased 1.6-fold[1]
%U http://www.biomedcentral.com/1471-2318/6/8