%0 Journal Article
%T Cosmetic Lifting Effect of a Formula Combining Tetrahydroxypropyl Ethylenediamine, Ononis Spinosa and Glycerin as Shown by a New 2-D Imaging Method
%A Romain Roure
%A Marion Lanctin
%A Alex Nkengne
%A Virginie Nollent
%J Journal of Cosmetics, Dermatological Sciences and Applications
%@ 2161-4512
%D 2013
%I Scientific Research Publishing
%R 10.4236/jcdsa.2013.33032
%X Facial sagging is a major aging change that affects the overall shape of the face. Sagging can negatively impact self-perception and consequently quality of life. In order to fight against this aging sign, we developed a combination of three active ingredients: Tetrahydroxypropyl Ethylenediamine (THPE), Ononis Spinosa extract and Glycerin. In a clinical study, we assessed the efficacy of this association on facial sagging and wrinkles, with a special focus on immediate and lasting effects. Thirty-nine women applied the tested product daily during an eight-week treatment period. Clinical grading by experts and a new, easy to operate, 2-D imaging method were performed at different time points. The 2-D imaging method measured the upper eyelid lifting effect. The results showed an immediate and significant improvement in sagging and wrinkle parameters; these benefits were still observed seven hours after the first application. Results also showed a significant long-term improvement. The lifting effect calculated from the 2-D pictures was 1.08 mm immediately after application; the same method showed a 1.80 mm lifting effect following the eight-week treatment period. These results suggest that a skin care product combining THPE, Ononis Spinosa and Glycerin properties may be used to reduce sagging as well as wrinkles with both immediate and long term benefits.
%K Facial Sagging
%K Wrinkles
%K Tetrahydroxypropyl Ethylenediamine
%K Immediate Effect
%K Long-Lasting Effect
%K 2-D Imaging
%K Lift Measurement
%U http://www.scirp.org/journal/PaperDownload.aspx?DOI=10.4236/jcdsa.2013.33032