%0 Journal Article
%T Evaluation of the Local Pediatric Renal Transplant Program ¨C A Single Centre Experience of M¨¹nster/Germany
%A B. Kranz
%A E. Kuwertz-Br£¿king
%A S. Fr¨¹nd
%A H. H. Wolters
%J Transplantationsmedizin
%D 2010
%I Pabst Science Publishers
%X Despite an improved conservative therapy of end stage renal failure, dialysis associated complications and diet restrictions are not compatible with the normal development of a child. Renal transplantation is the primary goal in the therapy of end stage renal disease in childhood. Due to the increasing number of patients on the waiting list and the lack of organs for transplantation each transplant centre has to optimize and to extend the renal transplant program.This study evaluated the local pediatric renal transplant program in Muenster/Germany between 1981 and 2009 with special regard to the differences between kidney transplantation before and after 1995.The data were taken from the local registry documented in the Eurotransplant ENIS program.Since 1981, 138 kidney transplantations were performed in 127 children younger than 18 years (mean age: 11.6 ¡À 4.5 years). Since 1995 an increase was documented in the number of kidney transplantations per year (3.6 to 6.2), the number of living related (31 versus 1) and pre-emptive transplantations (7 versus 2). The mean recipient age and the time on dialysis remained stable. Before 1995 the transplant survival after 1 and 5 years was 80.3% and 60.2%, respectively. Thereafter the transplant survival improved to 96.8% (p=0.025) and 80.4% (p=0.015).In summary an increase of pediatric kidney transplantations was documented. Living related and pre-emptive renal transplantation has been established without decreasing the time on dialysis. The 1 and 5 year transplant survival have clearly improved.
%K renal transplantation
%K children
%K dialysis
%K waiting time
%K complications
%U http://www.transplantation.de/fileadmin/transplantation/txmedizin/txmedizin_2010_2/09_kranz.pdf