%0 Journal Article
%T Evaluation of the Rationality of Fixed Dose Combinations of Cardiovascular drugs in a Multispecialty Tertiary care hospital in Coimbatore, Tamilnadu, India
%A Manjula Devi.A.S*
%J Hygeia : Journal for Drugs and Medicines
%D 2012
%I 
%X Plan: To assess theRationality of Fixed dose combinations (FDC) of Cardiovascular drugs in amultidisciplinary hospital in Coimbatore, India Prologue: Rationality of fixed dose combinations (FDC) containingcardiovascular drugs is one of the controversial and debated problems intoday¡¯s health care practice. Research in this field has not been flourishedand limited data are available regarding rationality of fixed dosecombinations. A prospective and descriptive study was conducted in thecardiology and general medicine department of a 550 bedded multi-specialtytertiary care teaching hospital for a period of six months.Methodology: The rationality was assessed using seven-point criteria.Hundred prescriptions were analyzed during the study period which included 606cardiovascular drugs. Of these, 21.78% were cardiovascular fixed dosecombinations. The most commonly prescribed combinations were aspirin +clopidogrel (38.63%) followed by furosemide + spironolactone (15.9%) andtelmisartan + hydrochlorothiazide (12.88%). There were 18 different fixed dosecombinations of cardiovascular drugs. Among the combinations, 35.71% wererational with respect to all the seven criteria with a scoring of 14 (100%). Around11.11% combinations scored 13 while 55.56% scored 8 - 12 and 5.56% scored 7.Outcome: The results indicated that most of the prescribedcardiovascular FDCs in the multidisciplinary tertiary care hospital selectedwere rational and found to comply with the seven point criteria scale.Keywords: Fixed dose combinations (FDC), cardiovascular drugs &prescriptions, seven point scale assessment.
%K Fixed dose combinations (FDC)
%K cardiovascular drugs &prescriptions
%K seven point scale assessment.
%U http://www.hygeiajournal.com/Downloads/13721030766.pdf