%0 Journal Article
%T Evaluation of Phoenix dactylifera fruits for Antiurolithiatic activity
%A Challa Srinivas Reddy
%A Pradeep Vardhaman
%J Hygeia : Journal for Drugs and Medicines
%D 2013
%I 
%X Plan:Phoenix dactylifera L. of Arecaceae (Palmae) family isconsumed worldwide as an edible fruit. Reviews indicated the use of fruit asantioxidant, anticancer, antilipaemic and antidiabetic in many traditional treatments.In the present study the antiurolithiatic activity of P. dactylifera fruits are reported.Materials and Methods: Then-Butanol and Aqueous extract preparations were made and administered as test compounds,Cystone as reference standard in five groups. Ethylene glycol induced hyperoxaluria is selected as a screeningmethod for induction of kidney stones and the levels of creatinine, urea and uricacid are analysed.Outcome: The n-butanol and aqueous extracts of P. dactylifera fruitsin the doses of 200mg/kg reduced creatinine, urea, uric acid levels,significantly in comparison with thecontrol. But both the extracts showedresults less than the standard drug 'Cystone' and the n-butanol extract wasmore effective than aqueous extract to decrease urea and uric acid levels.Among these two extracts the n-butanol extract exhibited more antiurolithiaticactivity.Keywords: Phoenix dactylifera, Ethylene Glycol, Urea, Uric Acid,Antiurolithiatic Activity.
%K Phoenix dactylifera
%K Ethylene Glycol
%K Urea
%K Uric Acid
%K Antiurolithiatic Activity.
%U http://www.hygeiajournal.com/Downloads/105424010518.Pradeep%20Vardhaman%20FINAL.pdf