%0 Journal Article %T Efecto del extracto acuoso de Aloe vera (L.) N. L. Burm. sobre indicadores lip赤dicos de suero de conejo Effect of the water extract from Aloe vera (L.) N. L. Burm. on rabbit serum lipids %A Juana Till芍n Cap車 %A Marjorie Fern芍ndez Nieves %A Rosa Men谷ndez Castillo %A Carmen Carrillo Dom赤nguez %J Revista Cubana de Plantas Medicinales %D 2008 %I ECIMED %X INTRODUCCI車N: trabajos realizados con extracto acuoso y gel hojas de Aloe vera (L.) N. L. Burm., administrados a ratones en un modelo de hiperlipidemia aguda inducida con trit車n, demostraron un efecto protector al incremento de los l赤pidos. OBJETIVOS: estudiar el efecto de la administraci車n a dosis repetida de extracto acuoso de A. vera sobre los indicadores lip赤dicos de suero de conejo. M谷TODOS: conejos machos Nueva Zelandia fueron tratados con extractos acuosos de A. vera a las dosis de 17 y 34 mg/kg de peso corporal, sobre la base de s車lidos totales durante 6 semanas, tambi谷n se incluy車 un grupo control sin tratamiento, el peso corporal, colesterol total, HDL-colesterol, LDL colesterol y triglic谷ridos fueron determinados al inicio y al final del per赤odo del experimento. RESULTADOS: se encontr車 una disminuci車n significativa del colesterol, LDL colesterol y triglic谷ridos en suero de los animales tratados con la dosis de 34 mg/kg de extracto acuoso al final del experimento, pero el HDL-colesterol no mostr車 variaciones. CONCLUSI車N: la administraci車n de extracto acuoso de A. vera a conejo durante 6 semanas caus車 una disminuci車n significativa de los l赤pidos en suero. INTRODUCTION: the research works conducted with water extract and gel from Aloe vera (L.) N. L. Burm., administered to mice in a triton-induced acute hyperlipidemia pattern, showed a protective effect against the increase of lipids. OBJETIVES: to study the effect of administration of water extract from A. vera at repeated doses on the lipid indicators of rabbit serum. METHODS: male New Zealand rabbits were treated with water extracts from Aloe vera at doses of 17 and 34 mg/kg of bodyweight, on the basis of whole solids for 6 weeks. An untreated control group was included. Body weight, total cholesterol, HDL-cholesterol, LDL cholesterol and triglycerides were determined at the beginning and at the end of the experimental period. RESULTS: it was found that cholesterol, LDL cholesterol and triglycerides significantly decreased in serum of animals treated with 34 mg/kg dose of the water extract at the end of the experiment, however, the HDL-cholesterol did not show any variation. CONCLUSIONS: the administration of water extract from Aloe vera to a rabbit for 6 weeks significantly reduced serum lipids. %K Aloe vera %K extractos acuosos %K colesterol %K LDL-colesterol %K triglic谷ridos %K conejos %K Aloe vera %K water extracts %K cholesterol %K LDL-cholesterol %K triglycerides %K rabbits %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-47962008000400009