%0 Journal Article
%T Cloisonn¨¦ kidney in mouflon sheep (<i>Ovis orientalis musimon</i>)
%A Herv¨¢s
%A J.
%A Chac¨®n-M. de Lara
%A F.
%A Azorit
%A C.
%J Pirineos : Revista de Ecolog¨ªa de Monta£¿a
%D 2002
%I Consejo Superior de Investigaciones Cient¨ªficas
%X This study describes a case of cloisonn¨¦ kidney associated with infection by Babesia ovis in a wild mouflon (Ovis orientalis musimonj found dead in year in eastern Sierra Morena (Andalusia, Spain). The major macroscopic lesions were a) icteric coloration in ocular and oral mucosa, and b) dark metal coloration on the kidneys' external surface. Intense dark coloration alternating with intense greyish strips was observed on renal cortex sections. Blood samples were collected for haematological and parasitological analyses, as well as samples from various organs for histopathological examination. Infection by B. ovis was confirmed by using the Polymerase Chain Reaction test (PCR). Histopathological examination revealed tubulonephrosis associated with thickening of the basal membrane of the convoluted portions of the renal tubules (both proximal and distal), which took on an intense brownish pigmentation. These renal lesions have been described as "cloisonn¨¦" kidney. Cloisonn¨¦ kidneys show uncommon coloring of the renal tubular system, associated with ferritin and hemosiderin deposits in these structures resulting from a chronic hemolitic process (hemoparasites, toxins, etc.). In our case, hemolitic phenomena are associated with infection by B. ovis. The seroprevalence of this hemoparasite in wild mouflon populations in other regions of Spain (Catalonia) is up to 15%. [fr] Nous ¨¦tudions un cas de rein cloisonn¨¦ associ¨¦ ¨¤ l'infection par Babesia ovis sur un mouflon sauvage (Ovis orientalis musimon) qui a ¨¦t¨¦ trouv¨¦ la m¨ºme ann¨¦e dans la partie orientale de la Sierra Morena (Andalousie, Espagne). Les principales l¨¦sions macroscopiques ¨¦taient: a) coloration ict¨¦rique sur les muqueuses oculaire et orale, et b) coloration m¨¦tallique fonc¨¦e sur la partie ext¨¦rieure du rein. Cette coloration fonc¨¦e intense alternait avec des bandes grisatres dans les sections du cortex r¨¦nal. Nous avons pris des ¨¦chantillons de sang pour les analyses h¨¦mathologique et parasitologique, ainsi que d'autres ¨¦chantillons de divers organes pour l'analyse histopathologique. L'infection pr B. ovis ¨¦tait confirm¨¦e par le test de la r¨¦action en cha ne de Polymerase (PCR). L'analyse histopathologique a r¨¦v¨¦l¨¦e une tubulonephrose associ¨¦e avec l¡¯¨¦paississement de la membrane basale des portions en boucle des tubules r¨¦naux (aussi bien proximaux que distaux), lesquels prenaient une intense pigmentation brunatre. Ces l¨¦sions r¨¦nales ont ¨¦t¨¦ d¨¦crites comme rein "cloisonn¨¦". Le rein cloisonn¨¦ montre une coloration extraordinaire du syst¨¨me r¨¦nal tubulaire, associ¨¦ avec un d¨¦p t de ferritine et h¨¦m
%U http://pirineos.revistas.csic.es/index.php/pirineos/article/view/73/73