%0 Journal Article
%T Prevalencia del h赤gado graso no alcoh車lico en muestras de biopsias hep芍ticas Prevalence of non-alcoholic fatty liver in samples of hepatic biopsies
%A Marlene P谷rez Lorenzo
%A Niuvisvey Duarte Castillo
%A Teresita Montero Gonz芍lez
%A Silvia Franco Estrada
%J Revista Cubana de Medicina Militar
%D 2006
%I ECIMED
%X Se realiz車 un estudio retrospectivo observacional de las biopsias hep芍ticas realizadas en el Instituto Superior de Medicina Militar ※Dr. Luis D赤as Soto§ en un periodo de 3 a os, y se descart車 mediante un estudio minucioso de las historias cl赤nicas la presencia de causas de da o hep芍tico graso secundario (v赤rales, t車xicas, quir迆rgicas y por alteraciones cong谷nitas del metabolismo). Se encontr車 que el 36 % de las biopsias correspond赤a con el diagn車stico de h赤gado graso no alcoh車lico. En todas sus formas histol車gicas se observ車 que el 52 % de los sujetos mayores de 45 a os mostraron las formas evolutivas histol車gicas m芍s severas (tipo III, IV). Se evidenci車 que existe estrecha relaci車n entre el h赤gado graso no alcoh車lico con los estados que conforman el denominado s赤ndrome de resistencia a la insulina (obesidad, hiperlipidemia, diabetes e hipertensi車n) y que la enfermedad tiene una evoluci車n silente .Se concluye que el h赤gado graso no alcoh車lico resulta una entidad prevalente en este medio, y como se espera un crecimiento proporcional de los h芍bitos que condicionan su g谷nesis, resulta necesario tener en cuenta dicho diagn車stico y la realizaci車n de la biopsia hep芍tica en aquellos casos de riesgo, con vistas a tomar una conducta terap谷utica que se dirija al control de los factores que lo condicionan. An observational and retrospective study of the hepatic biopsies performed in ※Luis D赤az Soto§ Higher Institute of Military Medicine during a period of 3 years was conducted, and the presence of secondary fatty hepatic damage (viral, toxic, surgical, and due to congenital disorders of the metabolism) was discarded by means of a detailed study of the medical histories. We found that 36 % of the biopsies corresponded to the diagnosis of non-alcoholic fatty liver. In all its histological forms, it was observed that 52 % of the subjects over 45 years old showed the most severe evolutional types (type III, IV). It was proved that there is a close relationship between the non-alcoholic fatty liver and the states composing the so-called ※resistance syndrome§ to insulin (obesity, hyperlipidemia, diabetes and hypertension), and that this disease has a silent evolution. It is concluded that non-alcoholic fatty liver is a prevalent entity in this environment, and as a proportional increase of the habits conditioning its genesis is expected, it is necessary to take into account this diagnosis, and to perform hepatic biopsies in those risk cases in order to follow a therapeutical conduct aimed at controlling the factors making it possible.
%K H赤gado graso no alcoh車lico
%K esteatohepatitis
%K enfermedad por dep車sito de grasa
%K Non-alcoholic fatty liver
%K steatohepatitis
%K disease due to fat deposit
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572006000400006