%0 Journal Article
%T Role of slow pathway after nodal fast pathway ablation on the basic and rate- dependent properties of the isolated rabbit atrioventricularNode
%A vahid khori
%A mohsen nayebpour
%A abbas mirabbasi
%A mona pourabouk
%J Physiology and Pharmacology
%D 2009
%I Iranian Society for Physiology and Pharmacology
%X Introduction : The aim of this study is to obtain new insight into possible relation between functional properties of slow concealed pathway and rate-dependent properties of AV-node.   Methods : Rate-dependent nodal properties of recovery, facilitation, and fatigue were characterized by stimulation protocols in one groups of (N=7) isolated superfused AV-Nodal rabbits. Small miniature lesions were made by delivering constant voltage (110 V-100 s) with unipolar silver electrode.   Results : Fast pathway ablation significantly decreased facilitation and had no effect on fatigue and nodal refractoriness. The most important effect of fast pathway ablation was prolongation of minimum conduction time.   Conclusion : The FP-ablation revealed the presence of the concealed SP. Rate-dependent property of node is dependent to dynamic interaction between concealed slow with slow pathway. Fast pathway involved in the mechanism of facilitation.
%K ablation
%K AV node
%K Fast pathway
%K arrhythmia
%U http://www.phypha.ir/ppj/browse.php?a_code=A-10-245-2&slc_lang=en&sid=1