%0 Journal Article
%T Efectos sist谷micos de la aplicaci車n del n-butil 2-cianoacrilato en la microcirug赤a vascular experimental Systemic effects of the application of n-butyl 2-cyanoacrylate on experimental vascular microsurgery
%A Juan Carral Novo
%A Galina Gueorguievna Rozhkova
%A V赤ctor Rodr赤guez Sosa
%A Caridad Sebazco Pernas
%J Revista Cubana de Medicina Militar
%D 2006
%I ECIMED
%X Se evalu車 la utilidad del n-butil 2-cianoacrilato en microcirug赤a vascular, se compar車 la evoluci車n en el cierre de las heridas vasculares, y se analiz車 el comportamiento visceral y hematol車gico. se realiz車 un estudio prospectivo aleatorio de cohorte (1 y 6 meses) en 65 ratas Wistar macho: controles sanos (n= 10), estudio (n= 28) y controles positivos (n= 27). Se aplic車 cianoacrilato en aorta abdominal con 3 puntos de retenci車n. Se compar車 la evoluci車n con la sutura cl芍sica con el polipropileno 8/0, se estudi車 repercusi車n histol車gica visceral y sangu赤nea. Hubo evoluci車n similar mediante ambos m谷todos, d egradaci車n del cianoacrilato a los 6 meses. La aplicaci車n del adhesivo no repercute en la evoluci車n de los casos ni produce toxicidad. The usefulness of n-butyl 2-cyanoacrylate in vascular microsurgery was assessed, the evolution in the closure of vascular wounds was compared, and the visceral and hematological behaviour was analysed. A cohort randomized prospective study was performed (1 and 6 months) in 65 male Wistar rats: sound controls (n= 10), study (n= 28), and positive controls (n= 27). Cyanoacrylate was applied in the abdominal aorta using three retention stitches. The evolution was compared with the classic suture with polypropylene 8/0. The histological, visceral, and blood repercussion was studied. There was a similar evolution by using both methods. Degradation of cyanoacrylate was observed at 6 months. The utilization of the adhesive neither influence on the evolution of the cases, nor produce toxicity.
%K Cianoacrilatos
%K microcirug赤a
%K cirug赤a vascular
%K Cyanoacrylates
%K microsurgery
%K vascular surgery
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-65572006000400002