%0 Journal Article
%T DIRECTIONS IN THE EVOLUTION OF CERVICAL L-SIL LESIONS
%A Bozidar Jovanovic
%A Miroslav Folic
%A Marko Folic
%A Momcilo Djordjevic
%J Acta Medica Medianae
%D 2005
%I The Faculty of Medicine in Nis
%X Molecular activities in the basic cytopathological substratum of the lesions on utherus cervicus, in case of HPV infection in form of squamous intraepithelial lesions of the low (L - SIL) and high (H - SIL) level, are defined by bathesda therminological system. More frequent, L - SIL changes include CIN I, coil atypia and condilomata lata and can be recognized by cellular abnormalities in the basal and parabasal layer with minor cellular structural changes , nuclei hyperhromasia with hromatin condensation, acantosis, paraceratosis with well differentiated cells and faster exfoliation. Women more prone to develop L-SIL are those older than 41, with III degree of vaginal secretion, with the colposcopic finding of aceto-white epithelium and Papa-Nicholaus test of III group. The control cervical, colposcopically controlled biopsy was resumed after four control medical check-ups done every three months after the L-SIL diagnosis. The results showed that lesions remained at the same stage (41,67%), whereas regression appeared in every third examinee (33,33%), slight progression in every eight examinee (12,50%), and significant progression in every twelfth examinee (8,33%).Our conclusion was that L-SIL lesions do not require the ablativ therapy a priory, and what is needed is a regular colpocytological check-up every three months and cervical biopsy, if necessary. Diagnosis of HPV infection certainly changes one¡¯s attitude and requires loop diameter because of the additional diagnostic indications and final therapy.
%K cervix
%K L-sil lesions
%K evolution
%U http://publisher.medfak.ni.ac.rs/2005-html/1-broj/2-rad/Directions%20in%20the%20evolution%20of%20cervical%20l-sil%20lesions.pdf