%0 Journal Article %T Linfoma no Hodgkin tipo anapl芍sico de localizaci車n cut芍nea: Presentaci車n de 1 caso %A Mar赤a Dolores Castillo Men谷ndez %A Eunice D赤az de Villegas 芍lvarez %A Magdalena Vigueras Fajardo %A Manuel Sabat谷s Mart赤nez %J Revista Cubana de Medicina %D 2003 %I ECIMED %X Se describi車 un caso de linfoma maligno no Hodgkin tipo anapl芍sico (LMnH), de localizaci車n principal en la piel de la regi車n tor芍cica posterior de un paciente de 56 a os de edad, masculino, raza negra, proveniente de la provincia de Manica, Mozambique. El cuadro lesional y topogr芍fico hizo pensar en otros tipos de tumores o micosis profundas. Se corrobor車 el diagn車stico de LMnH tipo anapl芍sico de grandes c谷lulas, CD 30+, por la histolog赤a, inmunocitoqu赤mica y la inmunohistoqu赤mica. Se inici車 el tratamiento con poliquimioterapia, CHOP (ciclofosfamida, doxorrubicina, vincristina y prednisona), 6 ciclos con intervalos de 3 semanas entre ellos. Se logr車 evoluci車n satisfactoria, la totalidad de las lesiones dermatol車gicas involucionaron. Actualmente, se encuentra en observaci車n. The case of a 56-year-old black male patient from the province of Manica, Mozambique, that presented an anaplastic malignant non-Hodgkin*s lymphoma mainly located in the skin of the posterior thoracic region, was described. The lesion and topographic picture made us think about other types of tumors or deep mycosis. The diagnosis of CD 30+ anaplastic malignant large-cell non-Hodgkin*s lymphoma was corroborated by histology, immunocytochemistry and immunohistochemistry. The treatment was initiated with combination chemotherapy, CHOP (cyclophosphamide, doxorubicin, vincristine and prednisone), 6 cycles at intervals of 3 weeks among them. A satisfactory evolution was attained. It was observed an involution of all the skin lesions. At present, this patient is under observation. %K LINFOMA NO HODGKIN %K LINFOMA DE GRANDES CELULAS %K QUIMIOTERAPIA COMBINADA %K LYMPHOMA %K NON-HODKING %K LYMPHOMA %K LARGE CELL %K DRUG THERAPY %K COMBINATION %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232003000100013