%0 Journal Article
%T THE INFLUENCE OF Ca-ASCORBATE ON CHANGING THE ILEUM SENSITIVITY
%A Voja Pavlovi£¿
%J Acta Medica Medianae
%D 2004
%I The Faculty of Medicine in Nis
%X In the case of previously mentioned Hartley guinea pigs, male gender, weight from 250 to 300 g, which lived under normal lab¡¯s conditions. The effect of different Ca-ascorbate concentrations was studied. Various Ca-ascorbate concentrations were used starting from 10-6 M to 10-1 M, while the sensitivity of thermal part of ileum was determined by Shultz-Dale¡¯s reaction.The samples of ileum treated by 10-5 M histamin and the received contraction has served as a maximal response (100%). Ileum sample was rinsed by Thyrode¡¯s solution, the media was exchanged by different contractions of Ca-ascorbate, and with the help of Shulzt-Dale¡¯s reaction, determined by the intensity of ileum contraction.The received results show that, with the growth of Ca-ascorbate concentration, from 10-6 M till 10-3 M. There is a mild growth of vitamin C concentration. This is in order to get 50% of response, and it¡¯s the greatest when 10-1 M Ca-ascorbate concentration is applied.These results show that the application of Ca-ascorbate lessons the sensitivity of thermal ileum part.
%K Ca-ascorbic
%K vitamin C
%K asscorbic acid
%K histamin
%K ileum
%K sensibilisation
%K Schultz-Dale-ova reaction
%U http://publisher.medfak.ni.ac.rs/2004-html/4-broj/UTICAJ%20CA-ASKORBATA%20NA%20PROMENU....pdf