%0 Journal Article %T Chemical composition and antimicrobial activities of the essential oils from three ecotypes of Zataria multiflora %A Zomorodian K %A Saharkhiz M %A Rahimi M %A Bandegi A %J Pharmacognosy Magazine %D 2011 %I Medknow Publications %X Background: Zataria multiflora Boiss. is a traditional and popular spice in Iran. The effects of 3 ecotypes (ECTPs) of Z. multiflora essential oils (EOs) against most common causes of food-borne and nosocomial infections were evaluated. Materials and Methods: The antimicrobial activities of the EOs were examined by broth microdilution method as recommended by the Clinical and Laboratory Standards Institute (CLSI). The chemical compositions of the EOs from 3 ECTPs of Z. multiflora have been analyzed by gas chromatography-mass spectrometry. Results: Analysis of the EOs indicated that 3 chemotypes were present in Z. multiflora, including carvacrol, thymol-carvacrol, and linalool, whereas previous studies have only found carvacrol and thymol. Inhibition studies showed that the tested EOs entirely inhibited the growth of yeasts at concentrations of less than 1 ¦ĚL/mL. Moreover, the oils exhibited significant bacteriostatic and bactericidal activities against Gram-positive and Gram-negative bacteria at concentrations ranging from 0.12 to 8 ¦ĚL/mL. Conclusion: These results suggest that the EOs from Z. multiflora should be investigated further for possible use in antimicrobial products and food preservatives. %K Antimicrobial activity %K chemotype %K carvacrol %K essential oil %K linalool %K thymol %K Zataria multiflora %U http://www.phcog.com/article.asp?issn=0973-1296;year=2011;volume=7;issue=25;spage=53;epage=59;aulast=Zomorodian