%0 Journal Article
%T Algunos factores de riesgo de la cardiopat赤a hipertensiva Some risk factors of hypertensive heart disease
%A Alexis 芍lvarez Aliaga
%A Julio C谷sar Gonz芍lez Aguilera
%J Revista Cubana de Medicina
%D 2009
%I ECIMED
%X Se realiz車 un estudio de casos y controles de pacientes con diagn車stico de hipertensi車n arterial, atendidos en la consulta especializada, para identificar si existe asociaci車n entre distintos factores hipot谷ticamente influyentes sobre el desarrollo de la cardiopat赤a hipertensiva. Los pacientes fueron tomados aleatoriamente 1:2 (300 casos: 600 controles). Se observ車 que la edad mayor o igual a 63 a os triplic車 el riesgo de padecer la enfermedad (OR 3,02; IC 95 % 2,27-4,03) y el tabaquismo lo duplic車 (OR 2,06; IC 95 % 1,55-2,73). Dentro de los biomarcadores de riesgo cardiovascular sobresalen la prote赤na C reactiva que eleva a m芍s de 13 el riesgo (OR 13; IC 95 % 9,70-19,3) seguido de la creatinina (OR 5,03; IC 95 % 3,37-7,51) y glucemia (OR 4,96; IC 95 % 93,61-6,81). El tiempo de evoluci車n de la enfermedad (OR 4,26; IC 95 % 3,18-5,72) el grado de hipertensi車n (OR 2,21; IC 95 % 1,65-2,96) y la falta de control de la hipertensi車n arterial (OR 2,16; IC 95 % 1,63-2,87), se comportaron como factores de riesgo. Se concluy車 con un an芍lisis de regresi車n log赤stica que mostr車 que la prote赤na C reactiva, el 芍cido 迆rico, la glucemia y la microalbuminaria son los factores de riesgo independientes m芍s importantes para el desarrollo de la enfermedad. A case-control study of patients diagnosed with arterial hypertension seen in specialized consultation was conducted to identify if there is a association among different supposedly influential factors on the development of the hypertensive heart disease. Patients were selected in a random way 1:2 (300 cases: 600 controls). Patients aged over or equal to 63 tripled the risk to suffer the disease (OR 3.02; CI 95 % 2.27-4.03) and smoking double it (OR 2.06; CI 95 % 1.55-2.73). Within the cardiovascular risk biomarkers are the reactive C protein raising the risk to more than 13 (OR 13; CI 95 % 9.70-19.3) followed by creatinine (OR 5.03; CI 95 % 3.37-7.51) and glycemia (OR 4.96; CI 95 % 93.61-6.81). Disease course time (OR 4.26; CI 95 % 3.18-5.72), hypertension degree (OR 2.21; CI 95 % 1.65-2.96), and lack arterial hypertension control (OR 2.16; CI 95 % 1.63-2.87) were the risk factors. We conclude with a logistic regression analysis showing that reactive C protein, uric acid, glycemia and microalbuminuria are the more significant independent risk factors for the disease development.
%K Hipertensi車n arterial
%K cardiopat赤a hipertensiva
%K factores de riesgo
%K Arterial hypertension
%K hypertensive heart disease
%K risk factors
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232009000400002