%0 Journal Article %T Regresi車n de hipertrofia ventricular izquierda con inhibidores de la enzima de conversi車n de angiotensina %A Joaqu赤n Sell谷n Crombet %A Iliana Cabrera Rojo %A L芍zaro D赤az P谷rez %A Gerardo Gallardo Montes de Oca %J Revista Cubana de Investigaciones Biomˋˋdicas %D 1996 %I ECIMED %X Se valor車 la regresi車n de la hipertrofia ventricular izquierda en hipertensos esenciales tratados con inhibidores de la enzima de conversi車n de angiotensina durante 6 meses. Se estudi車 anatom赤a y funci車n del coraz車n por ecocardiograma. Treinta y nueve pacientes culminaron el tratamiento. Se observ車 predominio del sexo femenino, raza blanca, con edad promedio de 47 a os. El 13 % fueron hipertensos ligeros, 51 % moderados y 36 % severos. Las cifras de presi車n arterial descendieron significativamente (p < 0,00001). En el ecocardiograma disminuyeron del ventr赤culo izquierdo: masa, 赤ndice de masa, pared posterior, septum y estr谷s meridional. La hipertrofia conc谷ntrica fue la m芍s frecuente, seguida de remodelaci車n conc谷ntrica. A los 6 meses alcanz車 geometr赤a normal el 12,83 % de la muestra. Se concluye que la monoterapia con estos f芍rmacos es efectiva para controlar la hipertensi車n arterial y provoca regresion anat車mica del crecimiento ventricular en un corto per赤odo. An assessment was made on the regression of left ventricular hypertrophy in essential hypertensive patients treated with angiotensin-converting enzyme inhibitors during 6 months. The heart anatomy and function were studied by echocardiogram. Thirty nine patients finished the treatment. Feminine sex and white race, with an average age of 47 years old, were prevailing. The 13 % were mildly hypertensive; 51 % were moderately hypertensive, and 36 % were severe. The figures of arterial pressure significantly decreased (p < 0,00001). At the echocardiogram, mass, mass index, posterior wall septum and meridional stress, decreased from the left ventricle. The concentric hypertrophy was the most frequent, followed by concentric remodeling. Six months later, the normal geometry was reached in the 12,83 % of the sample. It is concluded that monotherapy with these drugs is effective to control arterial hypertension, and it causes the anatomical regression of the ventricular growth in a short period. %K HIPERTROFIA VENTRICULAR IZQUIERDA %K HIPERTENSION %K INHIBIDORES DE LA ENZIMA CONVERTIDORA DE ANGIOTENSINA %K ECOCARDIOGRAFIA %K INTRODUCCION %K HYPERTROPHY %K LEFT VENTRICULAR %K HYPERTENSION %K ANGIOTENSIN-CONVERTING ENZYME INHIBITORS %K ECHOCARDIOGRAPHY %U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-03001996000100003