%0 Journal Article
%T Review: GOLD NANOPARTICULATE DRUG DELIVERY SYSTEM: A REVIEW
%A Nikunj Trivedi*
%A Niket Patel
%A U M Upadhyay
%A Viral Shah
%J Pharmacie Globale : International Journal of Comprehensive Pharmacy
%D 2012
%I 
%X Gold nanoparticles (AuNPs) are currently playing a significant role for human welfare in the field of clinical diagnosis as well as several biomedical applications. More and more research shows that AuNPs-based technologies are becoming promising approaches in cancer research and AIDS treatment. Gold nanoparticles (AuNPs) are a suitable platform for development of efficient delivery systems. AuNPs can be easily synthesized, functionalized, and are biocompatible. The tunability of the AuNP monolayer allows for complete control of surface properties for targeting and stability/ release using these nanocarriers. Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. With these systems, the gold core imparts stability to the assembly, while the monolayer allows tuning of surface properties such as charge and hydrophobicity. An additional attractive feature of AuNPs is their interaction with thiols, providing an effective and selective means of controlled intracellular release. This review will discuss several delivery strategies utilizing AuNPs.
%K gold nanoparticles
%K AuNPs
%K nanocarriers
%K gene delivery
%K cancer therapy
%U http://pharmacie-globale.info/index.php?option=com_docman&task=doc_view&gid=270&tmpl=component&format=raw&Itemid=41