%0 Journal Article
%T Mecanismos fisiopatol車gicos del desbalance glom谷rulo-tubular en la hipertensi車n arterial Pathophysiological mechanisms of the lack of glomerulus-tubule balance in arterial high blood pressure
%A Mar赤a Ofelia Barber Fox
%A Katiana Galvizu D赤az
%A Aydel赤n P谷rez Ramos
%A Mar赤a Ofelia Fox Pascual
%J Revista Cubana de Investigaciones Biomˋˋdicas
%D 2010
%I ECIMED
%X Las actuales tendencias e hip車tesis para interpretar los mecanismos etiopatog谷nicos de la hipertensi車n arterial esencial, involucran al sistema renal como mecanismo preponderante en la regulaci車n a largo plazo de la presi車n arterial y la existencia en 谷l de alg迆n fen車meno que puede conllevar a desbalance glom谷rulo-tubular, con preponderancia tubular Aunque el an芍lisis de este 迆ltimo hecho no ha sido como tal abordado en la patog谷nesis del s赤ndrome hipertensivo. Con el objetivo de interpretar el papel del desbalance glom谷rulo-tubular, con preponderancia tubular en la fisiopatolog赤a de la hipertensi車n arterial como fen車meno en el que confluyen m迆ltiples mecanismos fisiopatol車gicos renales ya descritos, se revisaron estos 迆ltimos, de forma integrada y su relaci車n causal con el desbalance glom谷rulo-tubular, con preponderancia tubular. La preponderancia tubular, punto com迆n de los mecanismos que se discuten, favorece la disminuci車n de la excreci車n fraccional de Na+, la retenci車n hidrosalina y la elevaci車n de la presi車n arterial. The current trends and hypotheses to know the etiopathogenesis mechanisms of the essential arterial high blood pressure involved the renal system as a prevailing mechanism in the long-term regulation of arterial pressure and the existence in it of some phenomenon that could lead to a glomerulus-tubule lack of balance with tubular preponderance. Although the analysis of this latter fact, has not been approached as such in pathogenesis of hypertensive syndrome. With the aim of to interpret the role of glomerulus-tubule lack of balance with tubular preponderance in pathophysiology of arterial high blood pressure as a phenomenon in which converging multiple renal pathophysiological mechanisms already described, these latter were reviewed in a integrated way and its causal relation with the above mentioned lack of balance with tubular preponderance. This preponderance, a common point of discussed mechanisms, favors the decrease of a fractional releasing of Na+, the hydrosaline retention and the raise of arterial pressure.
%K desbalance glom谷rulo tubular
%K hipertensi車n arterial y ri 車n
%K funci車n tubular e hipertensi車n
%K Tubular-glomerular lack of balance
%K arterial high blood pressure and kidney
%K tubular function and high blood pressure
%U http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-03002010000400007